Here we describe the development of a new set of tools that enable detailed analysis of regulatory pathways in living cells. SwitchGear Genomics has produced a library of thousands of human promoters, UTRs and other regulatory elements contained within a state-of-the-art luciferase reporter vector, the pGL4.11[luc2P] Vector. This library combines the ability to gather highly reproducible data over a broad dynamic range with the ability to scale to hundreds or thousands of promoters in a single experiment.
Promega Notes 96, 8–10.
Nathan D. Trinklein and Shelley Force Aldred