- Gene Overview
- Interaction Network
- Sequence Verification
GRP, gastrin releasing peptide
-
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
-
Gene Synonyms (gastrin-releasing peptide, bombesin, neuromedin C, pre-progastrin releasing peptide, prepro-GRP, testicular tissue protein Li 103, BN, GRP-10, preproGRP, proGRP,)
- NCBI Gene ID:
2922
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>A0A140VJM7
UNIPROT ID#>>P07492
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
gastrin releasing peptide interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|