STR-Analyse
Aussagekräftige STR-Systeme zur Zell- und Gewebeidentifizierung, humanspezifische Identitätstests und Identifikation gemischter Proben. Die Anwendungen beinhalten genetische Krankheitserforschung, Zell-und Gewebe-Herkunftsbestimmungen, Floater Analyse, mütterliche Zellidentizifierung, Krebsforschung, Zwillings-Zygotie-Tests, forensische Analysen und Vaterschaftsbestimmungen.
Cell Line and Sample Identification Product Groups
Top Cell Line Authentication Products for Your Lab
An Introduction to Cell Line Authentication
Short tandem repeat (STR) analysis is an informative approach to genetic identification that is commonly associated with DNA testing in forensic laboratories, paternity and missing persons cases. STR analysis is also used to verify tissue sample origins, authenticate cell lines, and detect tissue or cell mixtures.
STR profiling is a standard procedure for cell line authentication (ANSI/ATCC ASN-002). Cell line authentication provides researchers with confidence that their cell lines are correctly identified, and not cross contaminated with other cells. Major repositories now authenticate cell line identity, and many publications also require authentication of cell lines prior to publication of papers.
STR analysis is also used to confirm tissue identification. Any uncertainty as to a tissue’s origin must be resolved before the sample can be used in an experiment. STR analysis is a fast and easy way to do this. Researchers can compare the STR profile of the tissue with that of a reference sample to determine identity.
Likewise, STR analysis can be used to detect sample contamination, which appears as a mixed STR profile. The sensitivity of STR analysis, which can create full profiles from less than 100pg DNA, allows detection of minute quantities of contaminating cells or tissue.
